Estrogen Control of Uterine Glucose Metabolism
نویسندگان
چکیده
منابع مشابه
Estrogen Control of Uterine Glucose Metabolism AN ANALYSIS BASED ON THE TRANSPORT AND PHOSPHORYLATION
During incubation in vitro, uterine tissue readily converts the nonutilizable sugar, Z-deoxyglucose-lJ4C, to P-deoxyglucose-6-PJ4C. This process appears to be analogous to transport and phosphorylation of glucose and is a sensitive measure of the activity in the early steps of uterine sugar metabolism. Nonradioactive 2-deoxyglucose-lJ4C and Dglucose show similar inhibition of 2-deoxyglucose-lJ4...
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Radiolabeled anti-estrogen cu-[4-pyrrolidinoethoxylphenyl4-methoxy-cY’-nitrostilbene ([3HlCI-628) of high specific activity (16 Cilmmol) and radiochemical purity (>95%) has been prepared by catalytic tritium-iodine exchange and purified by alumina column chromatography. Its interaction with estrogen receptors in immature (day 20 to 24) rat uterus is studied in vitro and in ho. [3H]CI-628 (CI) c...
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The retention of receptor. estrogen complexes (R. E) in the nuclei of uterine cells was studied. When nuclei from uteri exposed to estradiol (E,) are subjected to a single extraction with 0.6 M KC1 in Tris/EDTA buffer, only 70% of R. E, is removed, and the remaining 30% is extractable with absolute ethanol. Several methods for quantitation of R. E, in nuclear KC1 extracts were compared. It was ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1968
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)93239-4